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Eight Ebola patient in Nigeria will be handle with an experimental drug prognosticate Nano Silver , the Nigerien curate of wellness said , according to news report .
The drug was reportedly developed by a Nigerien physician exist overseas , and is being shipped to Nigeria ’s big city , Lagos . But the health minister of religion did not disclose the name of the doctor who develop the treatment , and little else is roll in the hay about it , the Wall Street Journal reported .
A microscopic view of the Ebola virus.
One possibility is that the drug is made from nanoparticles of silver , but it may also be made from other element , experts say . In any sheath , it ’s highly unlikely the medicine has ever been test against Ebola in nonhuman animals , experts say .
" I am suspect of the claim … of this being a feasible treatment forEbola virus , and I am worried that this will have more harm than safe , " said Dr. Amesh Adalja , an infectious - disease specialist and a senior associate at the University of Pittsburgh Medical Center ’s Center for Health Security . [ 5 Things You Should Know About Ebola ]
Experimental drugs
The current Ebola outbreak — the largest in history — has kill more than 1,000 multitude in West Africa . Because there is no approved vaccinum or intervention for Ebola , and the computer virus has a in high spirits fatality charge per unit , the World Health Organization decide this week that it wasethical to expend unproven drugsin the current irruption .
Two American health fear workers and a Spanish non-Christian priest receive doses of an experimental , antibody - base drug address ZMapp . ( The Americans are report to be better ; the priest has died . ) A Canadian ship’s company is donating 1,000 window pane of its observational drug to Liberia , and the U.S. Food and Drug Administration lifted a hold on using another drug , develop by Tekmira Pharmaceuticals . All of those drugs have been tested in nonhuman primates , and the Tekmira drug is proceed through initial safety trials in humans .
But the drug that Nigerian health officials plan to use is much less well known — and likely less tested — than any of these experimental compound , expert say .
Nano silver
No one has reported on what Nano Silver is made of , or how it works .
One hypothesis is that the drug uses petite — or " nano " — molecule of silver . There is some evidence that silver has antimicrobic attribute , say Dr. William Schaffner , a professor of preventive medicine and infective disease at Vanderbilt University Medical Center in Nashville , Tennessee .
But as far as taking it orally as medicine , " silver has been try out in various other circumstances against several different infections with very circumscribed burden , " Schaffner separate Live Science .
Adalja take down thatsilver coatingson seam railings , catheters and endotracheal tubes can suppress bacteria from colonise those surface . Silver is also added to certain topical antibacterial emollient , such suntan creams , to prevent contagion , he say .
But there ’s no peer - reviewed grounds that silver could help oneself a person infected with the Ebola computer virus , Adalja said . And if the drug were actually made of bantam silver nanoparticles , then the particle could potentially penetrate cells and " bring some havoc there , " Adalja total .
In the U.S. and elsewhere , the diet supplement colloidal silver medal is popular , although fuddle too much of the liquid flatware break can have an vile side impression : Colloidal silver can sprain people blue .
But it ’s possible that the phrase " nano ash grey " is just a catchy name for a totally different compound , Adalja enounce .
No animal testing
It ’s unlikely that Nano Silver has been essay in fauna infected with Ebola , Adalja said . In the United States , Ebolais fantastically heavily to gain access to : Anyone who handles live Ebola computer virus must go in one of a fistful of biosafety grade 4 ( BSL-4 ) laboratories , and must be cleared by both the FBI and the Centers for Disease Control and Prevention ( CDC ) to work with such a dangerous agent , Adalja aver .
Another reason to doubt the intervention ’s lustiness is that any success in Ebola research tend to be boastful news , he said . In other row , if Nano Silver were showing promise , it would likely not have just been noticed now .
" Most of the things that are fit on with Ebola are very well advertise , " Adalja differentiate Live Science .
Giving untried discourse to Ebola patients is a hazardous proposition , Schaffner said .
People may recall to themselves , " ' These are desperate circumstances . What ’s to lose ? ' " Schaffner say . " There ’s a terrific amount to lose . "
If the drug harm people , or are just useless , " the already shivering confidence in the health care system could be threatened , " Schaffner say .
Even focusing on more prove drugs could undermine the public health effort . Quantities of all the observational drug are scarce , and are no substitute for " tested and rightful " methods forstopping Ebola , Adalja articulate .
" That involves basic public health and hygiene , finding cases , reporting them and get over them , " Adalja say .
